0002.03: Editor's choice curated: Cancer Top: dental like Oral cancer (preventive and regenerative) treatment solutions

 Age of Truth (Truth Journal: 0002 year, 03 month, then day). Journal category: ORAL CANCER Space Annual release. 

Links given, so no copyright violation. Reference with a snapshot from the link to understand what it's about. 

Truth journal tagline (Hope) "Cancer and Dental Care in the 🚀 Space Age of Truth: Regenerative and Preventive Solutions" without deviating from these topics: and maybe over years can make impact inspiring like cancer cures field like touching the stars:-) thanks: The point is to keep people abreast of the latest happenings in research to enable progress.



1. A new era for treating high-risk neuroblastoma – research advances to look out for in 2024

24 APR 2024

It's an exciting time for research into high-risk neuroblastoma. Over the past year, multiple trials testing new treatments showed promising results, and in 2024, new trials are expected to open to further advance this research. We look at some of the latest advances and how they could change the outlook for children with neuroblastoma. https://www.icr.ac.uk/blogs/science-talk/page-details/a-new-era-for-treating-high-risk-neuroblastoma-research-advances-to-look-out-for-in-2024#:~:text=In%20early%202023%2C%20a%20major,in%20a%20protein%20called%20ALK.


Posted on 24 April, 2024 by Professor Louis Chesler and Dr Lizzie Tucker.


2. Humans May Be Able to Grow New Teeth Within Just 6 Years: https://www.popularmechanics.com/science/health/a60952102/tooth-regrowth-human-trials-japan/


2010: Dr. Jeremy Mao at Columbia University: Grows back in 9 weeks patent pending: https://inventions.techventures.columbia.edu/technologies/generation-of-tooth--2553


July 2024: Once the drug is ready for human testing, clinical trials will begin in July 2024. Once the drug's safety is established, the trial will focus on children aged 2 to 6 who exhibit symptoms of anodontia. The participants will receive one drug dose to see if it initiates tooth growth.

https://www.dentalproductsreport.com/view/how-far-are-we-from-regrowing-teeth-and-what-are-the-other-options-


3DATE: March 2024,

HEADING: Design of Bone Scaffolds with Calcium Phosphate and Its Derivatives by 3D Printing

ABSTRACT:This review article explores the design and fabrication of bone scaffolds using 3D printing technology, focusing on the use of calcium phosphate and its derivatives. The article discusses the importance of scaffold structures in bone tissue engineering, which serve as a framework for new bone growth. It covers various 3D printing techniques and materials, including bioceramics and biodegradable polymers, and emphasizes the role of calcium phosphate in enhancing the mechanical and biological properties of bone scaffolds. The article highlights the advancements in 3D printing methods and their potential for creating complex, patient-specific bone scaffolds that can improve outcomes in tissue regeneration.

LINK:https://www.sciencedirect.com/science/article/abs/pii/S1751616124000237


4. DATE:2024 Oct 15

HEADING: Yeast β-glucan-based nanoparticles loading methotrexate promotes osteogenesis of hDPSCs and periodontal bone regeneration under the inflammatory microenvironment

ABSTRACT:This study explores the potential of yeast β-glucan-based nanoparticles loaded with methotrexate (cBPM) for treating periodontitis, a challenging inflammatory disease that causes periodontal bone loss. The nanoparticles were shown to promote osteogenesis of human dental pulp stem cells (hDPSCs) and enhance periodontal bone regeneration in an inflammatory environment. The cBPM nanoparticles worked by transforming macrophages from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, thereby reducing inflammation and encouraging bone repair. The results suggest that cBPM could be an effective alternative strategy for clinical treatment of periodontitis by utilizing its anti-inflammatory and bone regenerative properties.

LINK:https://pubmed.ncbi.nlm.nih.gov/39048236/



5. Title of the article: A space-time Caputo fractional order and modified homotopy perturbation method for evaluating the pathological response of tumor-immune cells


Brief summary: This study explores the behavior of tumor-immune cell growth under the influence of chemotherapy, utilizing a Caputo fractional order model and a modified homotopy perturbation method (HPM) to solve a system of nonlinear differential equations. The analysis provides insights into the spatiotemporal pathological response of tumor-immune cells, revealing the significant impact of Caputo-fractional order on the system's dynamics. The study's findings suggest that this mathematical approach offers an effective and precise technique for understanding the complex interactions of tumor-immune cells, with important implications for cancer research and treatment optimization.


Date it was published: June 1, 2024

Link : https://www.clinicalkey.com/#!/content/1-s2.0-S2772442524000273?scrollTo=%23hl0012498



6. Title of the article: An artificial intelligence system for early prediction of breast cancer regression pattern during neoadjuvant chemotherapy


Brief summary: The article presents a study on the development of an artificial intelligence (AI) system designed to predict tumor regression patterns (TRP) in breast cancer patients undergoing neoadjuvant chemotherapy (NAC). Using a 3D U-Net model for automated tumor delineation and a 3D ResNet-50 model for imaging feature extraction, the AI system demonstrated high accuracy in predicting TRP across various molecular subtypes and tumor stages. The AI system could assist clinicians in adjusting NAC regimens and planning breast-conserving surgeries based on early TRP predictions.


Date it was published: 12 August 2024

Link:https://ascopubs.org/doi/10.1200/JCO.2024.42.23_suppl.3




Articles and updates are welcome to be sent to: care@drdhruv.com

Comments

Popular posts from this blog

LAST Edition OPEN DENTAL "Fenêtre" Newsletter: A WINDOW INSIDE:- Elite Dental club focused:- On better HEALTH Oral healthcare preventive movement awareness eternally for a better world

How to book a preventive care check-up or dental appointment?

Your aesthetic dentist