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  Title: Genetics of Oral Lichen Planus: Identifying prognosis values and novel therapeutic interventions   First author: Dr. Dhruv Subramanian Principal Investigator: Dr. Mitesh Shetty Co-authors: Dr. Achuth M Baliga, Dr. K. Srinivas, Manipal Hospitals, Department of Dental, Medical Genetics and Oncology Bengaluru, India, and Dr. Dhruv Dental Care (R &D India Dental) Acknowledgment: Dr. Somashekar, Dr. Rajashekar (Srivarshini), Dr. James Hartsfield Jr (University of Kentucky), Dr. Paula Bates (University of Louisville), Dr. Carlo Deep (Colgate)   BACKGROUND Oral Lichen Planus (OLP) is an inflammatory condition affecting the mucosal mouth surface and is often co-diagnosed with xerostomia. OLP  affects  0.5% to 2% of the population. Treatments for OLP are usually palliative to control the inflammatory state of the disease, requiring life-long supportive care. When not controlled, OLP can lead to the formation of precancerous lesions which in some cases progre

Can the dental pulp be regenerated? First author: Dr. Dhruv Subramanian Acknowledgement: Dr. Shagufta Parveen   The dental pulp is unmineralized oral tissue that has soft connective tissue, lymphatic, vascular, and nerve tissue in the root canal chamber, and root canals of teeth in the oral cavity. The dental pulp can be regenerated with stem cells after the mechanical preparation of the infected tooth that is the hypothesis. Dental caries and periodontal infections are two major causes of infection of the dental pulp which leads to root canal preparations with a crown in most cases or extraction of the tooth itself. A root canal treatment is done by first drilling the tooth or the infected dental caries with an airotor. Then, files like needles of different sizes are used to clean the root canals and the pulp chamber mechanically. After this, the canal is irrigated with hypochlorite, hydrogen peroxide, saline, and sometimes, chlorhexidine of low concentration. Laser sterilizat