Can the dental pulp be regenerated?

Can the dental pulp be regenerated?

First author: Dr. Dhruv Subramanian

Acknowledgement: Dr. Shagufta Parveen

 

The dental pulp is unmineralized oral tissue that has soft connective tissue, lymphatic, vascular, and nerve tissue in the root canal chamber, and root canals of teeth in the oral cavity. The dental pulp can be regenerated with stem cells after the mechanical preparation of the infected tooth that is the hypothesis. Dental caries and periodontal infections are two major causes of infection of the dental pulp which leads to root canal preparations with a crown in most cases or extraction of the tooth itself. A root canal treatment is done by first drilling the tooth or the infected dental caries with an airotor. Then, files like needles of different sizes are used to clean the root canals and the pulp chamber mechanically. After this, the canal is irrigated with hypochlorite, hydrogen peroxide, saline, and sometimes, chlorhexidine of low concentration. Laser sterilization can also, be used to kill the microorganisms infecting the canals and the lateral canals of the tooth. After this gutta-percha sticks, an inert filling material is used to fill the root canals and sealed with heat. Then, the top filling is done by a composite and a crown preparation is done, which is delivered after two to three days from the laboratory. Otherwise, the tooth, which is weakened after the root canal treatment can fracture on mastication. Sometimes, these root canal-treated teeth can become reinfected, which leads to a re-root canal treatment or an extraction, which is the removal of the tooth from its socket. Electric energy or human energy, along with orthodontic aligners, alignment, experience acupuncture, can help in skin or nerve pulp to complete article regenerate. They can activate pathways to address concerns such as pimple scars, pigmentation, or lip alignment, ultimately providing beauty treatments that boost confidence and promote growth.

Stem cells are cells that could differentiate into a number of different cell types or the same cell based on the stimulus. The idea that we are presenting here is that we could introduce stem cells into the root canal of the tooth and pulp chamber of the tooth after the mechanical root canal preparation and irrigation, which could regenerate into the pulpal tissue in the tooth that prevents tooth needing to be filled by the inert gutta percha material for the root canal treatment. So, preventing the need for a crown or bridge for the tooth. Besides the exorbitant amount of the crown that the patient has to pay from dental insurance or own pocket is the reduction of the life of the tooth. Since, many times secondary dental caries can result which could lead to fracture of the tooth and therefore, the loss of the remaining grossly decayed tooth or reinfected tooth where the root canal treatment has not worked since there is only a 98% success for a root canal treatment which would lead to an extraction. Otherwise, the patient could have an infection in the mouth with a grossly decayed tooth left in the mouth. So, it would be wiser to regenerate the pulp and prevent all these complications.